Right drug. Right dose. Right person.

In partnership with the Beneplan Benefits Cooperative

Rx Report® – Psychiatry tests are available for Beneplan plan members and eligible dependents.

If you have any questions, please call 1 (844) 943-0210 or email info@personalizedprescribing.com

How Does It Work?

The drug compatibility test provides you and your eligible dependents with testing that may help your doctor find the right dose of the right drug, the first time.

How Rx Report® – Psychiatry Test Can Help

• Could prevent adverse reactions and harmful side effects
• Less trial-and-error with new prescription drugs
• May save $ on medication wastage
• May reduce absences from work

The Science Behind It

We are all genetically unique, and so are our responses to medication.

The drug compatibility test works by identifying these unique genetic differences.

The test provides a pharmacogenetic (drug-gene interaction) report with recommendations that have been clinically validated by at least one of the two leading consortia:

• Clinical Pharmacogenetics Implementation Consortium (CPIC)
• Dutch Pharmacogenetics Working Group (DPWG)

All testing is conducted at a state-of-the-art genetic laboratory that operates under the current Good Laboratory Practice (cGLP) guidelines set by Health Canada.

Pharmacogenetics is the study of how our genes influence our response to medication. A compatibility test is a test that will determine your genetic unique Rx Report® – Psychiatry in the form of specific drug recommendations.

These drug recommendations can be used by your doctor to prescribe the right dose of the right drug on the first try. Because these recommendations are clinically validated, you can think of a compatibility test more like an allergy test rather than a traditional genetic test. Pharmacogenetic tests do not – and cannot – determine an individual’s risk of developing certain diseases.

Some drugs are toxic for you and in that case, you suffer a degree of discomfort but eventually you go back to your doctor complaining about the discomfort and your doctor changes the medication.

However, it is the drugs that are not effective, that you should be concerned with. You could be on a medication that silently is NOT working for you. The result could be serious. In these cases, a pharmacogenetics test could help! This test may improve your quality of life, or it may even save your life.

Before ordering your Rx Report® – Psychiatry Test, it is crucial that you read and fully understand both the Disclosures, Disclaimers, and Important Information section, and this section below on Informed Consent and Choices.

When you have read and fully understood all the concepts in these sections, you may order your Rx Report® – Psychiatry Test and fill out the Informed Consent form that will be available for download after purchase on the “Thank You” page. You may also download the form from the bottom of this page.

You must fill in and sign your Informed Consent form before your Rx Report® – Psychiatry Test sample kit is shipped to you.

If you have any questions about any of the information below, please call us at 1 (844) 943-0210 or email info@personalizedprescribing.com. Both methods are 100% confidential.

Access to Results (choose one):

• I request that the healthcare professional (doctor/pharmacist) whose information I provided to Personalized Prescribing Inc. be granted access to view my Rx Report® – Psychiatry report, OR
• I request that, ONLY I be granted access to view my results.

I understand that only a healthcare professional may interpret and utilize the report to improve my health outcome. I understand that I should never make any changes to my medication without first consulting my healthcare professional.

I consent to taking a Rx Report® – Psychiatry Test, provided by Personalized Prescribing Inc.

I consent to providing Personalized Prescribing Inc. with personal information, including portions or all of my medical history.

I consent to Personalized Prescribing Inc. assigning me a barcode for the purpose of removing my personal health information – including my name – from my DNA sample and genetic information.

I consent to providing Personalized Prescribing Inc. with a barcoded sample of my DNA, which will be collected by me or by my doctor, and which will be sent through the Canadian postage system to Personalized Prescribing Laboratory in Richmond Hill, Ontario, Canada.

I authorize Personalized Prescribing Laboratory, a certified genetic laboratory, to determine my genetic information from my DNA sample.

I authorize Personalized Prescribing Laboratory to provide Personalized Prescribing Inc. with my genetic information for the purpose of providing drug recommendations based on the information.

I authorize Personalized Prescribing Laboratory to store my DNA sample for 90 days or until the next internal proficiency testing date, whichever case is longer, in case additional testing is necessary.

I authorize Personalized Prescribing Laboratory to archive a digital file of my barcoded (anonymous) genetic information within their encrypted and firewalled database system for 25 years, according to regulations and recommendations from international accreditors CLIA (Clinical Laboratory Improvement Amendments) and CAP (College of American Pathologists), respectively.

I authorize Personalized Prescribing Inc. to prepare a Rx Report® – Psychiatry report based on my genetic information that contains my name, my barcode number, and my drug recommendations and/or my genetic information, depending on my choices provided in this informed consent document.

I understand that, as in all testing, there is a possibility of delay or error.

I understand that I can direct that my genetic information at Personalized Prescribing Inc. be destroyed, and that they will comply within a week of receiving my direction.

I agree to release Personalized Prescribing Inc., Personalized Prescribing Laboratory, and their representatives from liability for injury that may arise from collecting and testing my DNA sample, and from any effects or actions that the results of this test may have on me or any other individual. I agree that I have read and understood all the information presented in this document and have been given the opportunity to ask questions and have had my questions answered.

You must read this part to understand our process. If you decide to order a Rx Report® – Psychiatry test, you will be required to give informed consent and make certain important choices regarding your test.

Which Genes are tested?

At Personalized Prescribing Inc., we test 3 metabolic genes- CYP2D6, CYP2C19, and CYP2B6. Additionally, our comprehensive analysis includes testing for 106 SNPs across 58 predominantly pharmacodynamic genes.

Which Drugs are covered by these Genes?

At Personalized Prescribing, we provide recommendations for the drugs that have been clinically validated at the highest level by independent consortia on pharmacogenetics (CPIC & DPWG). This is done to prevent a “false positive” in which a gene that is not clinically validated may produce a result that is not accurate and may lead to a negative health outcome. However, in some cases, we may provide you with clinical annotations that have not yet reached the highest level of clinical validation by the above-mentioned independent consortia. In this case, we will disclose this information to you and your healthcare professional, and with very clear disclaimers.

The drugs that we provide recommendations for can be found on our searchable Drug List.

The Difference between Genetic Information and Drug Recommendations

There is a big difference between the terms “genetic information” and “drug recommendations”, particularly for the use of this Rx Report® – Psychiatry test.

“Genetic Information” refers to the actual genetic code found in DNA. We all have the same genes, but it is our unique variations in these genes that make us different. For the purpose of this Rx Report® – Psychiatry test, the term “genetic information” will refer to the unique genetic variations as determined by our laboratory from your DNA sample. These genetic variations are written as either a single mutation (ex. 1029A>C) or as a combination of mutations within the same gene, also called a haplotype (ex. *17). A haplotype is a combination of mutations within a gene.

“Drug Recommendations”, for the purpose of this Rx Report® – Psychiatry test will refer to the clinically validated recommendation provided by Clinical Pharmacogenetics Implementation Consortium (CPIC) or Dutch Pharmacogenetic Working Group (DPWG) for each particular drug covered by this test. Your genetic information (as defined above) is used to determine which drug recommendation to provide in your test results. Drug recommendations are not considered genetic information, as they do not contain any reference to your unique genetic code. An example of a drug recommendation would be, “Elevated CYP2C19 and normal CYP2D6 enzyme activity. Consider alternative drug NOT metabolized by CYP2C19. If a tricyclic is warranted, utilize therapeutic drug monitoring to guide dose adjustments”.

Patients taking the Rx Report® – Psychiatry test are entitled to receive any information about their health that is produced by the test (Healthcare Consent Act). However, test subscribers must understand the consequences of knowledge of any or all parts of their health information. Subscribers may request access to some or all of their information; in that case they are responsible for any and all consequences stemming from the information they obtain. Because of this, please read the next part of our disclosures and disclaimers very carefully.

Important Disclaimers for Anyone Considering Taking this Rx Report® – Psychiatry test:

Lab Testing:

Rx Report® – Psychiatry test is extremely accurate, and our laboratory is CAP certified (the highest level of accreditation for laboratories under the FDA). However, like all testing there is a small possibility of delay or error.

System Security

To the best of our ability, Personalized Prescribing Inc. will ensure that any and every system that we maintain control over remains completely secure. However, no system is 100% secure. We will never sell, share, or disclose your personal information, health information, or genetic information to anybody without your consent. However, it is extremely unlikely yet possible that your information could be taken from our system without our permission (i.e. hacked).

Knowledge of Your Genetic Information

Although the genetic information produced in this pharmacogenetic test does not confer any type of risk of developing a certain disease currently, there is a possibility that new scientific discoveries of the future could determine an association with the genetic information produced in this test and a risk of developing a certain disease.

Genetic Anti-Discrimination Act

Because of the Genetic Anti-Discrimination Act passed in April 2017, no person or entity may discriminate against any individual based on their genetic information.

Consult Your Doctor

Never make any changes to your medication without first consulting your doctor. There may be factors other than your genetics that affect your response to medication. Please share the results of this Rx Report® – Psychiatry test with your prescribing physician and your pharmacist. You may request that the report is not shared with you, but only shared with your healthcare professional.

Privacy and Confidentiality

All the information that you provide is kept private and confidential, and information is only used on an aggregate level (for research and statistical purposes) to improve our services, showcase medication response patterns via research publications, and inform the care of future patients. For example, healthcare professionals and researchers may want to know statistically, the percentage of patients with genetic variation who responded well to medication.