The Science
Genes Included in the Rx Report Test
Comprehensive genetic testing for personalized medication recommendations
The Science Behind Our Testing
How Genes Affect Drug Response
Personalized Prescribing Inc. examines both pharmacokinetic and pharmacodynamic genes related to drug response. These genes influence drug effectiveness and interaction within the body.
Some serve as direct drug targets where genetic variations impact binding and activity, while others indirectly influence response through metabolic pathways. We emphasize comprehensive genetic testing to ensure all factors affecting drug response receive consideration.
Evidence-Based Foundation
Testing recommendations derive from rigorous scientific research supported by peer-reviewed publications and recognized consortia including CPIC and PharmGKB, which hold regulatory authorization for categorizing gene-drug relationship data.
Tested Genes
Metabolism and Transport
- CYP2D6
- CYP2C19
- CYP2B6
- CES1
- ABCB1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC1A2
- TPH1
- TPH2
- IDO1
- TH
- DBH
- GAD1
- MAO-A
- MAO-B
- COMT
- MTHFR
Receptors in Brain
- HTR1A
- HTR1B
- HTR2A
- HTR2C
- HTR3A
- HTR3B
- HTR7
- DRD1
- DRD2
- DRD3
- DRD4
- ADRA2A
- ADRB1
- ADRB2
- GABAa
- GRIA1
- GRIN1
- GRIN2B
- GRIK4
Stress Response and Signaling
- IL1b
- IL6
- IL10
- TNFa
- NPY2
- CRHR1
- CHRNB2
- NR3C1
- NR3C2
- FKBP5
- BDNF
- ADGRL3
- CACNA1C
- SNAP25
- ACE
- CCK
- FAAH
- GNB3
- SERPINE1
- ADM
- MC4R
The Gold Standard in Psychotropic Pharmacogenetics
Personalized Prescribing is one of the few companies worldwide that tests for repeat alleles in SLC6A4, SLC6A3, MAO-A, and DRD4, widely recognized as the gold standard for psychotropic pharmacogenetic testing.
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Learn More About Our Testing
For detailed information about genetic variations analyzed, contact our team.