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Genetics and pharmacogenomics

From genetics 101 to liver enzymes, brain receptors and why a multi-gene panel beats a single gene.

A DNA test report on a white deskPart 1 of 8Understanding Your DNA, Genes, and How They Can Affect Medication ResponseYou don’t need to be a geneticist to understand your genes.A genetics researcher working at a laboratory table with a clipboardPart 2 of 8What Is Pharmacogenomics (PGx)? How Your Genes Can Affect Medication ResponsePharmacogenomics, often shortened to PGx, looks at how a person's genes may influence the way they respond to medications.A genetics researcher working at a laboratory table with a clipboardPart 3 of 8Gene Glossary| Gene | Function | |---|---| | ABCB1 | Helps control how some medications move across the blood-brain barrier.A DNA double helix rendered in bluePart 4 of 8What Are Liver Enzymes?Liver enzymes are genes process a medication after you take it.A scientist in a laboratory analysing genetic sequencing resultsPart 5 of 8What Are Brain Receptor Genes?Brain receptor genes are the targets of the psychiatric drugs. The target receptors (genes) influence how your brain and body respond to a medication.A scientist in a laboratory analysing genetic sequencing resultsPart 6 of 8How Our Genes Influence the Way We Respond to MedicationsPeople can take the same medication at the same dose and have very different experiences.A DNA test report on a white deskPart 7 of 8Why Look at Several Genes Instead of Just One?Mental health medications usually do not work through just one gene.A DNA double helix rendered in bluePart 8 of 8Can Genetics Tell Us Someone's Serotonin, Dopamine or Norepinephrine Level?However, genes can provide information about biological systems that influence:

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