Section
Medications
Profiles of psychiatric medications: what each one treats, how it works, side effects, interactions, and the genes that change the response.
SSRIs6
Citalopram and escitalopram are selective serotonin reuptake inhibitors, or SSRIs, used primarily to treat depression and anxiety disorders.
Fluoxetine is a selective serotonin reuptake inhibitor, or SSRI, used primarily to treat depression, obsessive-compulsive disorder and bulimia nervosa.
Fluvoxamine works mainly by increasing the availability of Serotonin. Its principal brain target is the Serotonin Transporter — SERT
Paroxetine is one of the established SSRIs, along with medications such as:
Vilazodone is an antidepressant used in Canada for the symptomatic treatment of major depressive disorder (MDD) in adults.
SNRIs3
Duloxetine is a serotonin-norepinephrine reuptake inhibitor, or SNRI, used to treat depression, generalized anxiety disorder and several chronic pain conditio
Levomilnacipran works by blocking two transporter proteins: NET — Norepinephrine Transporter and: SERT — Serotonin Transporter
Venlafaxine and desvenlafaxine are closely related SNRI antidepressants. In fact, desvenlafaxine is the major active metabolite of venlafaxine:
NDRI1
Bupropion is an antidepressant that primarily affects dopamine and norepinephrine rather than serotonin.
Other antidepressants2
Vortioxetine, best known by the brand name Trintellix, is an antidepressant used in Canada for the treatment of major depressive disorder in adults.
Tricyclic antidepressants2
Amitriptyline is a tricyclic antidepressant (TCA) used primarily for depression and, at lower doses, for several types of chronic pain and other conditions.
Nortriptyline, best known in Canada by the brand name Aventyl, is a tricyclic antidepressant (TCA) used primarily to treat depression.
MAO inhibitors1
Moclobemide is an unusual antidepressant because it belongs to the broader monoamine oxidase inhibitor family but differs substantially from older irreversibl
Anxiolytics1
Buspirone is a non-benzodiazepine anti-anxiety medication used primarily to treat generalized anxiety disorder (GAD).
Mood stabilizers1
Antipsychotics7
Aripiprazole is an atypical antipsychotic medication used to treat schizophrenia, bipolar disorder and several other psychiatric conditions.
Brexpiprazole is an atypical antipsychotic medication used to treat schizophrenia and, at lower doses, as an add-on treatment for major depressive disorder wh
Clozapine is an atypical antipsychotic medication used primarily for treatment-resistant schizophrenia—schizophrenia that has not responded adequately to othe
Haloperidol belongs to the older group of antipsychotics called: First-Generation Antipsychotics — FGAs or Typical Antipsychotics
Olanzapine is one of the established second-generation antipsychotics.
Quetiapine is a second-generation antipsychotic used to treat schizophrenia and bipolar disorder.
Risperidone can be very effective, but several adverse effects deserve particular attention:
Stimulants2
Amphetamine is a central nervous system stimulant used primarily to treat attention-deficit/hyperactivity disorder (ADHD).
Methylphenidate is one of the most widely used medications for ADHD.
Non-stimulant ADHD medications3
Atomoxetine is a non-stimulant medication used primarily to treat attention-deficit/hyperactivity disorder (ADHD) in children, adolescents and adults.
Clonidine is a non-stimulant medication that reduces excessive activity of the sympathetic—or “fight-or-flight”—nervous system.
Guanfacine is a: Selective α2A-adrenergic receptor agonist and: Non-stimulant ADHD medication.
